In their study “Pacemaker Explantation in Patients With Lyme Carditis,” Wamboldt and colleagues¹ describe two cases involving the removal of pacemakers in patients with Lyme carditis, which highlights the importance of including Lyme carditis in the differential diagnosis for high-degree AV block.
Furthermore, these cases demonstrate the “benefits of early device interrogation in patients who have been treated for Lyme carditis and received a pacemaker during their treatment,” the authors explain.
Lyme carditis can lead to cardiac arrhythmias and conduction disorders, most commonly atrioventricular (AV) blocks.
Case #1
“A 48-year-old woman presented with shortness of breath and dizziness secondary to complete heart block,” the authors write. “Given the presence of symptomatic bradycardia, she was transferred to a tertiary hospital for pacemaker implantation.”
She had a non-specific rash on her abdomen 3 months before symptom onset.
Lyme disease testing was positive.
Authors’ Takeaway: “Pacemaker explantation is a potential option for patients with treated [Lyme carditis] who have undergone proper testing to ensure that normal cardiac conduction has resumed.”
Case #2
A 58-year-old man presented with dizziness, syncope, headache and myalgia. “His initial electrocardiogram showed atrial fibrillation with slow ventricular response,” the authors write. “During his admission he experienced symptomatic pauses lasting 4 to 10 seconds.”
He also had a pacemaker implantation.
Lyme disease testing was positive.
Both patients were treated successfully with antibiotics.
Typically, Lyme disease patients with conduction problems are placed on a temporary pacemaker. In both of these cases, the patients were placed on a permanent pacemaker.
On follow-up, both pacemakers were functioning. “Both patients underwent exercise stress testing and were able to maintain 1:1 conduction at a heart rate >120 beats/min,” according to the authors.
The permanent pacemakers were removed successfully.
“Within the first year of insertion, transvenous lead extraction has a high success rate and a low complication rate,” the authors explain. The pacemaker is more difficult to remove if present over a year due to fibrotic changes.
“This highlights the importance of close follow-up so that early pacemaker explantation can be arranged if clinically indicated,” the authors suggest.
Related Articles:
Can we avoid using a pacemaker for Lyme carditis with high degree AV block?
Lyme disease and the heart, when AV block progresses rapidly
Mitral valve dysfunction from Lyme carditis
References:
- Wamboldt R, Wang CN, Miller JC, Enriquez A, Yeung C, Chacko S, Foisy M, Baranchuk A. Pacemaker Explantation in Patients With Lyme Carditis. JACC Case Rep. 2022 May 18;4(10):613-616. doi: 10.1016/j.jaccas.2022.02.012. PMID: 35615211; PMCID: PMC9125511.
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