In their article “Lyme neuroborreliosis: A case report,” Sayad and colleagues demonstrate that Lyme disease can, in fact, cause seizures. “Here, we present a case of neuroborreliosis with seizures as the first manifestation in a 55-year-old man.”¹
The patient was admitted to the emergency department with a sudden onset of tonic–clonic seizures. (This type of seizure, also referred to as a grand mal seizure, involves a loss of consciousness and violent muscle contractions.) The patient’s condition rapidly deteriorated and he was intubated.
His initial symptoms began 1 week prior to his hospitalization and included a mild headache, low-grade fever, malaise, anorexia, and vomiting.
Four days before hospitalization, he had his first seizure and was prescribed an anti-convulsive medication and antibiotic.
Routine laboratory tests were normal, except for a positive Wright and 2-mercaptoethanol test. As a result, the man was tested for Lyme disease.
“Our patient was suspected of neuroborreliosis due to aseptic meningitis with lymphocyte dominance. Hence, we requested serum anti-Borrelia antibodies (IgM and IgG) tests, both positive in high titers,” the authors wrote.
“The results of the serologic tests indicated the presence of both IgG and IgM antibodies to Borrelia burgdorferi,” the authors wrote.
The patient was treated successfully with IV ceftriaxone for Lyme disease and had a complete resolution of his seizures.
Authors’ Conclude:
- “Lyme neuroborreliosis can be difficult to diagnose unless it presents with typical symptoms and clinicians actively consider this diagnosis.”
- “It causes a wide range of neurological and psychiatric disorders.”
- “There is no gold standard test that can be relied upon for diagnosis.”
- “This illness can be successfully treated if treatment starts early with antibiotics.”
Related Articles:
Seizures and altered mental status after a tick bite
Neurologic complications of Babesia
Neurological damage/dysfunction in early Lyme disease patients
References:
- Sayad B, Babazadeh A, Barary M, Hosseinzadeh R, Ebrahimpour S, Afshar ZM. Lyme neuroborreliosis: A case report. Clin Case Rep. 2023 Aug 7;11(8):e7702. doi: 10.1002/ccr3.7702. PMID: 37554577; PMCID: PMC10405229.
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